Multidimensional Echocardiographic Parameters Predict Left Ventricular Functional Recovery After Coronary Artery Bypass Grafting.
In 214 patients undergoing first-time elective CABG at a single Chinese center, 59.8% achieved LV functional recovery (delta LVEF at or above 5% at 6 months).
Independent predictors were structural: LAVI, LVEDD, LVESD, LAD, SYNTAX score, and graft number.
Early postoperative delta LVEF predicted 6-month recovery with an AUC of 0.846, and recovery was independently protective against 1-year MACE.
The headline finding is the negative one: global longitudinal strain carried no independent predictive value in any LVEF subgroup.
AIM: This study aimed to investigate the predictive value of preoperative and early postoperative echocardiographic parameters for left ventricular function recovery after coronary artery bypass grafting (CABG), and to evaluate the relationship between functional recovery and 1-year clinical prognosis. METHODS: This retrospective cohort included 214 patients undergoing first-time elective CABG at The First Affiliated Hospital of Yangtze University between January 2022 and October 2024. Transthoracic echocardiography was performed preoperatively, 3-7 days postoperatively, and at 6 months to evaluate left ventricular ejection fraction (LVEF), global longitudinal strain (GLS), left atrial volume index (LAVI), and ratio of early mitral inflow velocity to early diastolic mitral annular velocity (E/e'). Based on 6‑month LVEF change, patients were divided into recovery (ΔLVEF ≥5%) and non‑recovery (ΔLVEF 0.05), whereas LAVI and LAD were significant predictors in patients with LVEF ≥40% (including the 40%-49% subgroup), but showed no predictive relevance in those with LVEF <40%. Early postoperative ΔLVEF predicted 6-month functional recovery with an area under the curve (AUC) of 0.846. After one year of follow‑up, the recovery group exhibited a markedly lower rate of MACE than the non‑recovery group, with left ventricular functional recovery serving as an independent protective factor against MACE. CONCLUSIONS: Preoperative structural parameters, including LAVI, LVEDD, LVESD, and LAD, are independent imaging biomarkers for predicting left ventricular functional recovery after CABG. GLS and E/e' ratio show no independent predictive value in this study. The integrated model combining clinical factors with multi-dimensional echocardiographic parameters demonstrates excellent discriminative ability. Early postoperative LVEF improvement strongly predicts 6-month functional recovery, while postoperative recovery of left ventricular function is associated with a significantly lower 1-year MACE risk.
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